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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NCL
All Species:
17.27
Human Site:
S153
Identified Species:
38
UniProt:
P19338
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19338
NP_005372.2
710
76614
S153
D
E
E
E
D
D
D
S
E
E
D
E
E
D
D
Chimpanzee
Pan troglodytes
XP_516145
1006
108719
S424
D
E
E
E
E
D
D
S
E
E
D
E
E
D
D
Rhesus Macaque
Macaca mulatta
XP_001116949
938
100743
S380
D
E
E
E
E
D
D
S
E
E
D
D
E
D
D
Dog
Lupus familis
XP_850477
699
75739
S137
D
E
E
D
D
D
D
S
E
E
E
D
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P09405
707
76705
D153
D
E
D
E
D
E
E
D
E
D
D
S
D
E
D
Rat
Rattus norvegicus
P13383
713
77129
D153
D
E
D
E
D
E
E
D
E
D
D
S
D
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509329
631
67414
D158
D
D
D
D
D
D
D
D
E
D
D
S
E
E
E
Chicken
Gallus gallus
P15771
694
75622
E124
E
E
E
D
E
D
D
E
D
D
E
E
D
E
D
Frog
Xenopus laevis
P20397
651
70177
S163
E
E
E
D
D
E
E
S
E
D
E
P
M
E
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797746
400
43419
V13
V
Q
K
K
S
K
G
V
K
T
V
E
Q
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27476
414
44517
A27
A
K
E
E
K
A
K
A
V
S
S
S
S
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
74.7
91.6
N.A.
83.9
84.2
N.A.
65.6
63.2
55.6
N.A.
N.A.
N.A.
N.A.
N.A.
24
Protein Similarity:
100
70.4
75.4
94.9
N.A.
90.1
90.4
N.A.
73.9
76
68.4
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
P-Site Identity:
100
93.3
86.6
73.3
N.A.
46.6
46.6
N.A.
46.6
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
93.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
64
10
28
37
55
55
55
28
10
46
55
19
28
28
64
% D
% Glu:
19
73
64
55
28
28
28
10
73
37
28
37
46
55
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
10
10
10
10
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
46
0
10
10
37
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
10
10
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _